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This item is an Rx medication or Food and requires a prescription. Once you place the order, the Pet360 Pharmacist will work directly with your veterinarian to verify the prescription and dosage information.

The medication for your pet will ship within one business day of verification. It will ship from the Pet360 Pharmacy in Louisville, Kentucky.

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Your pet may be prescribed Acepromazine if he/she needs tranquilization or if he/she suffers from motion sickness.

What is Acepromazine?This is a tablet that is given by mouth. It is used to sedate animals for minor procedures (e.g., nail trims). It can also be used as a pre-anesthetic and as an anti-emetic to prevent vomiting due to motion sickness. This medication is not a pain reliever (analgesic).

What are the benefits of Acepromazine?
  • Can be given by mouth to provided sedation.
  • Available in two sizes for more accurate dosing.
  • Can be useful in preventing vomiting due to motion sickness in some animals.

Formulated for:Dogs. Acepromazine is labeled for dogs but may be used off-label in other species.

How is this medication given?This medication is given by mouth. It is imperative that you follow your veterinarians exact directions regarding the use of this medication. If you do not understand how to use Acepromazine correctly, always consult with your veterinarian.

How does this medication work?Acepromazine is a tranquilizer that targets the central nervous system and depresses certain neurologic activities which results in sedation and muscle relaxation.

What results can I expect? It takes about one (1) hour for after oral acepromazine is given for it to reach its maximum effective. Acepromazine can last for up to 12 hours but it can vary from on animal to another. Some dog breeds including Collies, Australian shepherds, greyhounds and giant breeds may be more sensitive to this medication.

What form(s) does Acepromazine come in? This is a tablet that is given by mouth. An injectable liquid is also available.

Generic Name:Acepromazine(Common Drug Name)

Common Brand Name:PromAce

Dose and Administration:Give this medication orally exactly as prescribed by your veterinarian. Never give this medication to any animals other than the one it has been prescribed for unless you are directed otherwise. If you miss a dose, give it as soon as you remember if needed but never give two doses at once. If you are unsure of how to use this medication correctly, ask your veterinarian.

Uses:Acepromazine is used as a tranquilizer, sedative, and as a pre-anesthetic. It can also be used to prevent vomiting due to motion sickness.

Possible Side Effects: Side effects may include droopy eyelids with the third eyelid more exposed, incoordination, or slower heart rate and breathing. Your pet may have pink or reddish brown urine after acepromazine is used. Some pets may become hyperexcitable or aggressive with the use of this medication. Low blood pressure and inability to maintain proper body temperature is also possible. Other side effects may occur.

Drug and Food Interactions: Always tell your veterinarian about all medications and supplements your pet is taking. Interactions may occur with atropine, central nervous system (CNS) depressants (ex. barbiturates, narcotics, and antidepressants), organophosphate dewormers or insecticides, Kaopectate, Pepto-Bismol, antacids, propranolol, quinidine, phenytoin, and epinephrine. Other drug interactions are possible.

Precautions:Animals who allergic to this medication or other phenothiazines should not take it. Use with caution in debilitated or geriatric animals and those with liver or heart disease. Pregnant or lactating animals should not take this medication unless the benefits outweigh the risks. Animals with low blood volume, anemia, shock, tetanus, or strychnine toxicity should not take this medication. If your pet has a seizure history, he/she should not take acepromazine.

Storage:Store at room temperature away from children and pets.

A prescription from your veterinarian is required to purchase Acepromazine.

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by PowerReviews

(based on 3 reviews)

Ratings Distribution

  • 5 Stars



  • 4 Stars



  • 3 Stars



  • 2 Stars



  • 1 Stars




of respondents would recommend this to a friend.


No Pros


No Cons

Best Uses

No Best Uses
    • Reviewer Profile:
    • Long-time pet owner (3)

Reviewed by 3 customers

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This brand was not as effective as what I've used from vet.

By Chase G

from Dallas, TX

About Me Long-time Pet Owner



    • Not Effective

    Best Uses

      Comments about Acepromazine:

      We've used Acepromazine on my dog before. Obtained from my vet, in red pills. Same dosage ( 2 x 25mg). We usually see the effects within 2 hours, and we can really tell when it hits him. We actually needed him even more submissive and out of it go this last go around so we gave him (3 x 25mg) which is a LOT. For whatever reason, this brand of acepromazine had absolutely no affect on him. Tried again a couple days later with no success. Gave it to him in the morning, just to make sure we could see if it had any affect throughout the day. He was *a little* tired, but no where near as effective as the two red acepromazine pills we've given him from the vet. Extremely disappointed, wish I could get my money back.

      (3 of 5 customers found this review helpful)


      this is the best medicine for storms separation anxiety

      By Bruzer

      from Tamarac FL

      About Me Long-time Pet Owner


      • Easy To Administer
      • Effective
      • Gentle
      • Good Value


      • Makes Him Eat More Someti

      Best Uses

      • Larger Pets
      • Older Pets

      Comments about Acepromazine:

      use for storms we have lots of them here in FL, and if I'm going to be gone longer then a couple hours I give him a 1/2 just to take edge off and he knows it works when he feels a storm coming he goes to the cabinet where it's kept and barks, so my dog "Duke" know when he needs it too... best medication out there.

      (1 of 1 customers found this review helpful)


      Great Product For Active Pet

      By none

      from New Paltz,ny

      About Me Long-time Pet Owner

      Verified Reviewer


      • Easy To Use


        Best Uses

        • Short-Term Care
        • Younger Pets

        Comments about Acepromazine:

        Helps our Girl with Travel.

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